I remember to see a blogpost about this some time ago, but I can't find it.
It should be possible. ClojureCLR can generate "regular" .exe packages. If you know how to turn these exe's in WASM, you can try and see if there is some errors.
It should not be suitable to "websites", once it should generate huge bundles of wasm. But for "web applications", like a Game, can be a good solution.
