I think that multimethod metadata can be extended a bit with some property indicating the var in question is referring to a multimethod (we have something similar for macros) and some default arglists property.
I'm raising this issue because as a tool writer (CIDER) I'm having hard time determining if something is a multimethod (I have to resort to code like (instance? clojure.lang.MultiFn obj) which is acceptable, but not ideal I think (compared to macros and special forms)). There's also the problem that I cannot provide the users with eldoc (function signature) as it's not available in the metadata (this issue was raised on the mailing list as well https://groups.google.com/forum/#!topic/clojure/crje_RLTWdk).
I feel that we really have a problem with the missing arglist and we should solve it somehow. I'm not sure I'm suggesting the best solution and I'll certainly take any solution.