Vectors of primitives produced by {{vector-of}} do not support transients.
core.rrb-vector implements transient support for vectors of primitives. Such transient-enabled vectors of primitives can be obtained in a number of ways: (1) using a gvec instance as an argument to {{fv/catvec}} (if RRB concatenation happens, which is not guaranteed) or {{fv/subvec}}; (2) passing a gvec instance to {{fv/vec}}, which as of core.rrb-vector 0.0.11 will simply rewrap the gvec tree in an RRB wrapper; (3) using {{fv/vector-of}} instead of {{clojure.core/vector-of}}. Native support in gvec would still be useful as part of an effort to make supported functionality consistent across vector flavours (see CLJ-787 in this connection); gvec is also simpler and still has (and is likely to maintain) a performance edge.
A port of core.rrb-vector's transient support to gvec is available here:
https://github.com/michalmarczyk/clojure/tree/transient-gvec
I'll bring it up to date with current master shortly.
See the clojure-dev thread for some benchmarks:
https://groups.google.com/d/msg/clojure-dev/9ozYI1e5SCM/BAIazVOkUmcJ